Imidacloprid a me Moxidectin Spot-on Solutions (no nā ʻīlio)

【Mea Nui】

Imidacloprid, Moxidectin

【Ka nana aku】

Melemele a ʻeleʻele melemele wai.

【Phana harmacologic】

Laau antiparasitic.

Pharmacodynamics:ʻO ka imidacloprid kahi hanauna hou o ka nicotine insecticides. He affinity kiʻekiʻe no ka postsynaptic nicotinic acetylcholine receptors i loko o ke kikowaena nūnū nenoaiu o insects, a hiki ke keakea i ka hana o ka acetylcholine, alakai i ka parasite maʻi 'aʻai a me ka make. He mea maikaʻi ia e kūʻē i nā ʻauʻau makua a me nā ʻauʻau ʻōpio ma nā pae like ʻole, a he hopena pepehi hoʻi i nā ʻauʻau ʻōpio i ke kaiapuni. ʻO ke ʻano o ka hana o ka moxidectin ua like ia me ka abamectin a me ka ivermectin, a he hopena pepehi maikaʻi kona i nā parasites o loko a me waho, ʻoi aku ka nematodes a me nā arthropods. ʻO ka hoʻokuʻu ʻana o ka butyric acid (GABA) e hoʻonui i kona ikaika paʻa i ka postsynaptic receptor, a wehe ke kahawai chloride. Loaʻa i ka Moxidectin ke koho a me ka pilina kiʻekiʻe no nā glutamate-mediated chloride ion channels, no laila ke keʻakeʻa nei i ka hoʻouna ʻana i ka hōʻailona neuromuscular, hoʻomaha a hoʻomaha i nā parasites, e alakaʻi ana i ka make o nā parasites. ʻO nā interneurons inhibitory a me nā neurons motor excitatory i nā nematodes kona mau wahi o ka hana, ʻoiai ma nā arthropods ʻo ia ka hui neuromuscular. ʻO ka hui pū ʻana o nā mea ʻelua he hopena synergistic.

Pharmacokinetics:Ma hope o ka hoʻoponopono mua ʻana, ua māhele koke ʻia ka imidacloprid i ka ʻili o ke kino o ka ʻīlio i ka lā hoʻokahi, a noho mau ma ka ʻili o ke kino i ka wā o ka hoʻoponopono ʻana i nā lā 4-9 ma hope o ka hoʻoponopono ʻana, hiki i ka pae kiʻekiʻe o ka moxidectin i loko o nā ʻīlio. laha ʻia i loko o ke kino i loko o hoʻokahi mahina a ua hoʻololi mālie ʻia a hoʻokuʻu ʻia.

【Nā hōʻailona】
No ka pale ʻana a me ka mālama ʻana i nā maʻi parasitic kūloko a me waho i nā ʻīlio. Ka pale ʻana a me ka mālama ʻana i nā maʻi peʻa (Ctenocephalic canis), ka mālama ʻana i nā maʻi lice (Catonicus canis), ka mālama ʻana i nā maʻi ear mite (ltchy otica), canine sarcoids (Scabies mites), a me demodicosis (Demodex canis), no ka mālama ʻana iā Angiostrongylus a nā maʻi nematode gastrointestinal (nā pākeke, nā ʻōpio ʻōpio a me L4nā ʻōpala o Toxocara canis, Ancylostoma canis, a me Ancylocephalus larvae; nā mākua o Toxocara lionis a me Trichocephala vixensis). A hiki ke hoʻohana ʻia e like me ka adjuvant treatment of allergic dermatitis i hoʻokumu ʻia e nā fleas.

【Hoʻohana a me ka hoʻohana】
Forexternal hoʻohana, hoʻokuʻu i kēia huahana ma ka ʻili mai ke kua o ka ʻīlio ma waena o nā ʻāpana poʻohiwi ʻelua a hiki i ka ʻāʻī, a māhele iā ia i 3-4 mau wahi. Hoʻokahi pānaʻi, no nā ʻīlio, no ka 1kg o ke kaumaha o ke kino, 10mg o imidacloprid a me 2.5mg o moxidectin, e like me 0.1ml o kēia huahana. I ka wā o ka prophylaxis a i ʻole ka mālama ʻana, ʻōlelo ʻia e lawelawe i hoʻokahi manawa i ka mahina. Kāohi i nā ʻīlio mai ka palu ʻana.

【Ka hopena ʻaoʻao】

(1) I kēlā me kēia hihia, hiki i kēia huahana ke hoʻoulu i kahi hopena maʻi kūloko, e hoʻoulu ai i ka ʻeha transient, adhesion lauoho, erythema a luaʻi paha. Nalo kēia mau hōʻailona me ka mālama ʻole.

(2) Ma hope o ka lawelawe ʻana, inā liʻiliʻi ka holoholona i ka wahi lawelawe, hiki ke ʻike ʻia nā hōʻailona neurological transient, e like me ka hauʻoli, ka haʻalulu, nā hōʻailona ophthalmic (dilated pupil, pupillary reflexes, a me nystagmus), ka hanu ʻino, salivation, a me nā hōʻailona e like me ka luaʻi. ; i kekahi manawa, hiki mai ka hoʻololi ʻana i ke ʻano e like me ka makemake ʻole i ka hoʻoikaika kino, ka hauʻoli, a me ka pau ʻana o ka ʻai.

【Hoʻomalu】

(1) Mai hoʻohana i nā ʻīlio ma lalo o 7 pule o ka makahiki. ʻAʻole pono nā ʻīlio i maʻi i kēia huahana. Pono nā ʻīlio hāpai a me ka lactating e hahai i nā ʻōlelo aʻo holoholona ma mua o ka hoʻohana ʻana.

(2) Pono nā ʻīlio ma lalo o 1kg e hahai i nā ʻōlelo aʻo holoholona i ka wā e hoʻohana ai i kēia huahana.

(3) Aia kēia huahana i ka moxidectin (macrocyclic lactone), no laila, i ka wā e hoʻohana ai i kēia huahana ma luna o nā collies, nā ʻīlio hipa Pelekane kahiko a me nā ʻano like ʻole, pono e uku nui ʻia e pale i kēia mau ʻīlio mai ka palu ʻana i kēia.huahana ma ka waha.

(4) Pono nā ʻīlio maʻi a me nā ʻīlio nāwaliwali ke kino e hahai i ka ʻōlelo aʻo a nā kauka holoholona i ka wā e hoʻohana ai.

(5) ʻAʻole pono e hoʻohana ʻia kēia huahana i nā pōpoki.

(6) I ka wā e hoʻohana ai i kēia huahana, mai ʻae i ka lāʻau lapaʻau i ka paipu lāʻau e hoʻopili i nā maka a me ka waha o ka holoholona lawelawe a i ʻole nā ​​holoholona ʻē aʻe. Mai hoopa a oki i ka lauoho a maloo ka laau.

(7) ʻAʻole e hoʻopilikia nui ʻia ka hopena o ka lāʻau i ka 1 a i ʻole 2 o nā ʻīlio i ka wai i ka wā hoʻokele. Eia nō naʻe, ʻo ka hoʻohana pinepine ʻana i ka shampoo no ka ʻauʻau ʻana a i ʻole ka hoʻoinu ʻana i ka wai e nā ʻīlio e hoʻopilikia i ka maikaʻi o ka lāʻau.

(8) E mālama i nā keiki mai ka launa pū me kēia huahana.

(9) Mai waiho ma luna o 30℃, a mai hoʻohana ma mua o ka lā pau o ka lepili.

(10) ʻAʻole pono ka poʻe maʻi i kēia huahana.

(11) I ka lawelawe ʻana i ka lāʻau lapaʻau, pono e pale ka mea hoʻohana i ka pili ʻana me ka ʻili, nā maka a me ka waha o kēia huahana, ʻaʻole e ʻai, inu a uahi paha; ma hope o ka lawelawe ʻana, pono e holoi ʻia nā lima. Inā paʻi wale ia i ka ʻili, holoi koke me ke kopa a me ka wai; inā paʻi ʻole ia i ka maka, holoi koke me ka wai.

(12) I kēia manawa, ʻaʻohe lāʻau hoʻopakele kikoʻī no kēia huahana; inā ale hewa ʻia, hiki i ka lanahu hoʻōla waha ke kōkua i ka detoxification.

(13) Hiki ke hoʻohaumia i ka mea hoʻoheheʻe i loko o kēia huahana e like me ka ʻili, nā lole, nā plastik, a me nā ʻili pena. Ma mua o ka maloʻo ʻana o ka wahi hoʻoponopono, pale i kēia mau mea mai ka hoʻopili ʻana i ke kahua hoʻokele

(14) Mai ʻae i kēia huahana e komo i ka wai o luna.

(15) Pono e hoʻolei ʻia nā lāʻau lapaʻau i hoʻohana ʻole ʻia a me nā mea hoʻopili i kahi ʻano ʻino ʻole e like me nā koi kūloko.

【Hoihoi  manawa】ʻAʻohe

【Hōʻike】

(1)0.4ml:Imidacloprid 40mg +Moxidectin 10mg

(2)1.0ml:Imidacloprid 100mg+Moxidectin 25mg

(3)2.5ml:Imidacloprid 250mg +Moxidectin 62.5mg

(4)4.0ml:Imidacloprid 400mg+Moxidectin 100mg

 【Waihona】

Hoʻopaʻa ʻia, mālama ʻia ma ka lumi wela.

【Ola ola】

3 makahiki